Widely regarded as the most authoritative and comprehensive book in its field, the fourth edition of Fundamentals of Rock Mechanics includes new and substantially updated chapters to this highly praised text. Extensively updated throughout, this new edition contains substantially expanded chapters on poroelasticity, wave propogation, and subsurface stresses Features entirely new chapters on rock fractures and micromechanical models of rock behav ...
Carbonate cements are very common and abundant in clastic sequences. They profoundly influence the quality of hydrocarbon reservoirs and supply important information on palaeoenvironments and the chemical composition and flow patterns of fluids in sedimentary basins. Despite this importance, their distribution patterns in time and space and their geochemical evolution are not yet deeply explored and elucidated. This Special Publication contains ...
Man's complex relationship to planet Earth is explored in this second edition of the landmark anthology edited by Frank Rhodes and Bruce Malamud. This volume provides a portrait of the planet as experienced not just by scientists, but by artists, aviators, poets, philosophers, novelists, historians, and sociologists as well. A unique collection that bridges the gap between science and humanities Contains writings by scientists, artists, aviators ...
Soil Erosion and Conservation provides a comprehensive treatment of the processes of soil erosion, the methods that can be used for their control, and the issues involved in designing and implementing soil conservation programmes. Features of the third edition of this internationally recognised textbook include: New material on gully erosion, tillage practices, erosion risk assessment, use of erosion models, incentives for farmers and land users ...
It has been 10 years since publication of the first edition of Soils of the Past. In that time the subject of paleopedology has grown rapidly, and established itself within the mainstream of geological research. Ancient soils contain vital mineralogical, geochemical, textural, and paleontological information about the continental environments in which they formed. Advances in isotope geochemistry and sequence-stratigraphic models allow more deta ...
Written in a clear and concise style by an experienced author, this attractively-priced book covers regulatory affairs in all major global markets for pharmaceuticals and medical devices, making it the most comprehensive in its field. Following a look at drug development, complete sections are devoted to national and EU regulatory issues, manufacturing license application and retention, and regulation in the USA. Other topics dealt with include ...
As research on the human, animal, plant and microbial genomes matures towards descriptive fullness, the need for understanding the proteome has clearly emerged as the next major endeavor of life sciences. Proteomics – the quantitative analysis of all proteins working in a cell at a specific time and at specific conditions – provides deep insight into the highly organized network of expression, modification and degradation of proteins. Compiled i ...
Antisense and ribozymes have a relatively short yet successful history as research tools in gene expression studies, and thus are considered as having high potential reagents in treating viral infections and cancer. This laboratory companion provides detailed information on the potential, advantages and limitations of this methodology. It critically discusses potential pitfalls, presents strategies for choosing targets and delivery systems, so a ...
Here, expert scientists from industry and academia share their knowledge on the assembly of functional human tissues in vitro and how to design drug screenings predictive of human exposure. In so doing, they combine the latest technological developments with strategic outlooks, such as novel cell and tissue systems for drug screening and testing, as well as emerging in vitro culture technologies. Equally importantly, the book does not shy away f ...
