This new book, written by two outstanding scientists in the field, describes the basic principles of toxic mechanisms and organ toxicity, providing detailed information on specific mechanisms or chemicals for exemplification. The goal is to provide sufficient information that the reader becomes familiar with the basic concepts in toxicology to enable him or her to understand the basic principles in toxicology and to evaluate the risks at given e ...
First explaining the basic principles of liquid chromatography and mass spectrometry and then discussing the current applications and practical benefits of LC-MS, along with descriptions of the basic instrumentation, this title will prove to be the indispensable reference source for everyone wishing to use this increasingly important tandem technique. * First book to concentrate on principles of LC-MS * Explains principles of mass spectrometry a ...
Carbohydrates offer a ready source of enantiomerically pure starting materials. They have been used for the imaginative synthesis of a wide range of compounds, and have been found to be effective chiral auxiliaries which enable the introduction of a range of functionalities in a highly enantioselective manner. In a subject dominated by volumes at research and professional level, this book provides a broad understanding of the use of carbohydrate ...
Concentration on renewable resources, sustainability and replacement of oil based products are driving forces to reassess the potential of natural resources including natural colorants. The growing consumer interest in purchasing “green” products, which exhibit an improved environmental profile, can be seen as the break-through force needed to reintroduce natural colorants into the modern markets. Written by scientists with specialised knowledge ...
Fragment-based drug discovery (FBDD) is a new paradigm in drug discovery that utilizes very small molecules – fragments of larger molecules. It is a faster, cheaper, smarter way to do drug discovery, as shown by the number of pharmaceutical companies that have embraced this approach and the biotechnology companies who use fragments as their sole source of drug discovery. Fragment-Based Drug Discovery: A Practical Approach is a guide to the techn ...
Most modern surfactants are readily biodegradable and exhibit low toxicity in the aquatic environment, the two criteria for green surfactants. However the majority are synthesised from petroleum, so over the past decade the detergent industry has turned its attention to developing greener routes to create these surfactants via renewable building blocks. Surfactants from Renewable Resources presents the latest research and commercial applications ...
Recoverable and Recyclable Catalysts There is continued pressure on chemical and pharmaceutical industries to reduce chemical waste and improve the selectivity and efficiency of synthetic processes. The need to implement green chemistry principles is a driving force towards the development of recoverable and recyclable catalysts. The design and synthesis of recoverable catalysts is a highly challenging interdisciplinary field combining chemistry ...
The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers ...
Useful throughout history for their medical as well as other benefits, plant-derived compounds have gained particular importance recently, due to environmental factors. The isolation and characterization of plant products, the identification of their role in the plant, and ways of synthesizing identical compounds or more potent analogues are covered. Also includes methods of culturing plant tissues and genetic engineering as a means of increasin ...
