Gramicidin channels have been studied intensively for more than 25 years. They serve as model transport systems for large protein ion channels, since it is difficult to glean high-resolution structural information on the latter. This book includes contributions from virtually all the major scientists studying gramicidin channels and is the only compilation of work in this field. It discusses crystallographic, spectroscopic, electrophysiological ...
Helmut Sigel, Astrid Sigel and Roland K.O. Sigel, in close cooperation with John Wiley & Sons, launch a new Series “Metal Ions in Life Sciences”. The philosophy of the Series is based on the one successfully applied to a previous series published by another publisher, but the move from “biological systems” to “life sciences” will open the aims and scope and allow for the publication of books touching on the interface between chemistry, biology, ...
This book features contributions from experts in cell biology, genetics, neurobiology, immunology and structural biology. The unifying element is that they all study processes of cell shape change and motility. Several key questions in this field of research are discussed: What are the organising principles behind cell shape change? Are there ‘master switches’ present in every cell type? How are extracellular signals interpreted by the cell in o ...
Praise for From Alchemy to Chemistry in Picture and Story «The timeline from alchemy to chemistry contains some of the most mystifying ideas and images that humans have ever devised. Arthur Greenberg shows us this wonderful world in a unique and highly readable book.» —Dr. John Emsley, author of The Elements of Murder: A History of Poison «Art Greenberg takes us, through text and lovingly selected images, on a 'magical mystery tour' of the chemi ...
Regulation of transcription represents a major, controlling step in plant gene expression, as it determines the tissue-specific and developmental stage-specific activity of many genes. Changes in gene expression have been shown to underlie the responses to environmental cues and stresses, the response against pathogens, the regulation of metabolic pathways, and the regulation of photosynthesis, for example. Regulation by transcription factors is ...
Unique in approach, exhaustive in coverage: this book provides information usually not available to scientists. It explains the basic scientific and technical requirements which apply to the patenting and registration of human or veterinary vaccines and therapeutic biomedicinal products. Pragmatic and practice-oriented, it helps users select and manage successfully the most attractive research and development projects. An impressive number of to ...
Biochemical analysis is a rapidly expanding field and is a key component of modern drug discovery and research. Methods of Biochemical Analysis provides a periodic and authoritative review of the latest achievements in biochemical analysis. Founded in 1954 by Professor David Glick, Methods of Biochemical Analysis provides a timely review of the latest developments in the field. ...
The use of cell-based assays within pharmaceutical and biotechnology companies is driven in large part by the need to evaluate the plethora of drug targets derived from genomics and proteomics. In addition, the potential of biomarkers to facilitate the development of effective and safe drugs is being recognized as an integral part of all phases of drug development, and cell-based technologies are a critical part of biomarker discovery and develo ...
Мультипериодический закон эволюции – междисциплинарный, касается всего микро-, макро- и мегамира и аналогичен (гомологичен) закону Д. И. Менделеева по большим, средним и малым гармоникам цикличности. В биологии статистически обнаружена такая же сложная периодичность, состоящая из множества гармоник цикличности фено- и геноизменчивости среднего индивидуума, когорт поколений вида, рода и их следствий. Выявленный мультипериодический закон является ...
