This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis of multiple ligand-target interactions. The ready reference opens with a general introduction to the use of mass spectrometry in pharmaceutical screening, followed by a detailed description of recently developed analytical systems for use in the pharmaceutical laboratory. Applications ran ...
Bei der Herstellung von Produkten und Verbrauchsgutern in verfahrenstechnischen Produktionsanlagen ist die Kristallisation ein wesentlicher Verfahrensschritt, um bei Stofftrennprozessen eine hohe Reinheit zu erzielen. Diese Stofftrennungsschritte verursachen haufig einen gro?en Teil der Anlagenbetriebs- und Investitionskosten. Das Buch vermittelt auf klare und verstandliche Weise die Planungsgrundlagen und Beurteilungskriterien fur Kristallisati ...
A guide for younger R&D chemists as to how they can quickly evolve skills built around three factors – people, knowledge and time. It covers the management of scientific personnel, management within a variety of R & D organizational structures, creating a climate of innovation, the management of projects including the time management and communication aspects of the job. As such, it teaches the vital managerial aspects of scientific jobs in indu ...
This first comprehensive handbook on the subject describes the manufacturing processes of various types of papers, recovered paper treatment, as well as the quality and economical aspects. More than 20 authors contribute a variety of viewpoints, one of the many features of this book. They give a concise description of the fascinating art and technology of papermaking, providing lay readers, students, politicians and others with the latest inform ...
Get a good start in flavor and fragrance chemistry! This book presents a survey of those natural and synthetic fragrance and flavor materials which are commercially available, produced and used on a relatively large scale and which are important ingredients for the creation of fragrance and flavor compositions because of their specific sensory characteristics, e.g., smell, taste. It provides information on their properties, methods employed in t ...
Covering the important task of the scale-up of processes from the laboratory to the production scale, this easily comprehensible and transparent book is divided into two sections. The first part details the theoretical principles, introducing the subject for readers without a profound prior knowledge of mathematics. It discusses the fundamentals of dimensional analysis, the treatment of temperature-dependent and rheological material values and s ...
The rational, structure-based approach has become standard in present-day drug design. As a consequence, the availability of high-resolution structures of target proteins is more often than not the basis for an entire drug development program. Protein structures suited for rational drug design are almost exclusively derived from crystallographic studies, and drug developers are relying heavily on the power of this method. Here, researchers from ...
Mastering management skills is hard to achieve by newcomers starting their careers in the chemical industry. The message coming from there is that good chemists swiftly have to become good managers if they are to survive and progress in today's competitive climate. This book is designed to help guide younger R & D chemists to ways in which they can quickly evolve skills which are built around three factors – people, knowledge and time. It covers ...
Peptides are among the most versatile bioactive molecules, yet the do not make good drugs, because they are quickly degraded or modified in the body. To overcome this problem, stable and at the same time biologically active pseudo-peptides have been developed. These novel compounds open up new perspectives in drug design by providing an entire range of highly specific and non-toxic pharmaceuticals. This is the first work devoted to the topic and ...
