When Wittig first developed and described phosphorus ylides, nobody could have imagined how useful and versatile this class of compounds could be. This book provides a comprehensive and up-to-date compilation of the chemistry and applications of phosphorus ylides in organic synthesis. The ylides are discussed as reagents in the synthesis of a broad range of substances, amongst them olefins, acetylenes, cyclic and heterocyclic compounds, in such ...
The story of success goes on and on – with a new book on combinatorial chemistry, edited by Gunther Jung! Combinatorial chemistry is a proven time- and resource-saving synthetic method of outstanding importance for industrial processes. Compound libraries help to save time and money, especially in the search for new drugs, and therefore play a pivotal role in solving the problem of the worldwide increasing demand for new and more active drugs. N ...
The new edition of this practice-oriented handbook features thoroughly updated contents, including recent developments in parallel synthesis. A new chapter on screening complements the overview of combinatorial strategy and synthetic methods. «Experimental details and complete reaction data […] are a constant theme running through this work» (Angewandte Chemie) «Recommended to newcomers in the field of combinatorial chemical synthesis because of ...
Filling the gap in the literature, this book presents everything there is to know about this topic. By comprehensively covering the quaternary stereocenters found in a range of important and useful molecules in pharmaceutical and medicinal applications, as well as in thousands of natural products, the book provides the know-how chemists need to synthesize challenging molecules with numerous applications. A must for organic chemists in academia, ...
For the first time, the whole field of organoboronic acids is presented in one comprehensive handbook. Professor Dennis Hall, a rising star within the community, covers all aspects of this important substance class, including applications in chemistry, biology and medicine. Starting with an introduction to the structure, properties, and preparation of boronic acid derivatives, together with an overview of their reactions and applications, the bo ...
This first book on this fascinating topic is edited by one of today's most famous and internationally respected organic chemists, renowned for his pioneering synthesis of the cyclopropenyl cation. For his part, Ronald Breslow has brought together leading scientists in this expanding area to provide a novel overview of protein-, cyclodextrin-, metal- and porphyrin-based artificial enzymes as well as enzyme-like polymers and dendrimers. A must for ...
At long last: The second, completely revised edition of this comprehensive standard reference. Alwyn G. Davies has updated the contents of his book to reflect the current state of research into organotin chemistry. He covers all aspects in detail, such as its synthesis, characterization, structures and applications, while also devoting space to such hot topics as environmental issues. This new edition also includes a CD-ROM with more than 5,000 ...
Acetylenes are an important and valuable class of compounds in organic synthesis. This book expands on this historically well-established concept, while incorporating the many new developments that have widened the number of applications in this field. It remains the only handbook available that embodies all the important facets of acetylene chemistry. Following the first section on synthesis, the leading authors deal with advanced materials bef ...
In the very first book on this hot topic, the expert editors and authors present a comprehensive overview of these elegant reactions. From the contents: Organoboron compounds Free-radical mediated multicomponent coupling reactions Applications in drug discovery Metal catalyzed reactions Total synthesis of natural products Asymmetric isocyanide-based reactions The Biginelli reaction Asymmetric isocyanide-based reactions The Domino-Knoevenagel-Het ...